BIIB 014
| CAS No. | 442908-10-3 | Cat. No. | BCP15984 |
| Name | BIIB 014 | ||
| Synonyms | BIIB-014;BIIB014;Vipadenant;CEB4520; V-2006; | ||
| Formula | C16H15N7O | M. Wt | 321.34 |
| Description | Vipadenant showed excellent binding affinity for A2A and had modest selectivity against A1 and A2B (Ki = 63 nM), while it showed good selectivity against A3 (Ki = 1005 nM). Vipadenant was able to increase contralateral rotations in 6-OHDA lesioned rats when dosed orally in combination with apomorphine at 3 and 10 mg/kg. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Adenosine Receptor | ||
Structure
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