BPTES

  • Chemical Properties
CAS No. 314045-39-1 Cat. No. BCP15991
Name BPTES
Synonyms
Formula C24H28N6O2S3 M. Wt 528.71
  • Biological Activity
Description BPTES is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. BPTES has a K(i) of approx. 3 microM. BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex.
Pathways Others Pathway 
Targets Others 

Structure

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