HA 130

  • Chemical Properties
CAS No. 1229652-21-4 Cat. No. BCP15986
Name HA 130
Synonyms HA-130;HA130;
Formula C24H19BFNO5S M. Wt 463.29
  • Biological Activity
Description HA130 is a potent and selective autotaxin (ATX) inhibitor (IC50 = 28 nM). HA130 slows T cell migration across lymph node HEVs in vivo. Ex vivo, HA130 blunts the TEM-promoting activity of ATX, paralleling its in vivo effects.
Pathways Protease/Metabolic Enzyme 
Targets Phosphodiesterase/PDE 

Structure

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