HA 130
CAS No. | 1229652-21-4 | Cat. No. | BCP15986 |
Name | HA 130 | ||
Synonyms | HA-130;HA130; | ||
Formula | C24H19BFNO5S | M. Wt | 463.29 |
Description | HA130 is a potent and selective autotaxin (ATX) inhibitor (IC50 = 28 nM). HA130 slows T cell migration across lymph node HEVs in vivo. Ex vivo, HA130 blunts the TEM-promoting activity of ATX, paralleling its in vivo effects. | ||
Pathways | Protease/Metabolic Enzyme | ||
Targets | Phosphodiesterase/PDE |
Structure
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