Cefbuperazone

  • Chemical Properties
CAS No. 76610-84-9 Cat. No. BCP16025
Name Cefbuperazone
Synonyms BMY-25182; T-1982; BMY 25182; T 1982; BMY25182; T1982;
Formula C22H29N9O9S2 M. Wt 627.65
  • Biological Activity
Description Cefbuperazone is a semisynthetic second-generation cephalosporin with antibacterial activity. Cefbuperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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