Baricitinib trifluoroacetate
| CAS No. | 1187594-10-0 | Cat. No. | BCP16048 |
| Name | Baricitinib trifluoroacetate | ||
| Synonyms | INCB028050;INCB 028050;INCB-028050;LY3009104;LY-3009104;LY 3009104; | ||
| Formula | C16H17N7O2S | M. Wt | 371.42 |
| Description | Baricitinib, also known as INCB 028050 or LY 3009104, is an orally administered selective JAK1 andk JAK 2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK 2( 5.7 nM). It also inhibits intracellular signaling of multiple proinflammatory cytokines including IL-6 and IL-23 at concentration less than 50 nM. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| Targets | JAK | ||
Structure
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