YN968D1 Hydrochloride
| CAS No. | 1218779-89-5 | Cat. No. | BCP16050 |
| Name | YN968D1 Hydrochloride | ||
| Synonyms | Apatinib Hydrochloride;YN968D-1 Hydrochloride;YN968D 1 Hydrochloride; | ||
| Formula | C24H24ClN5O | M. Wt | 433.93 |
| Description | Apatinib, also known as YN968D1, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VEGFR RET | ||
Structure
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