YN968D1 Hydrochloride
  • 化学数据
CAS号 1218779-89-5 货号 BCP16050
中文名 YN968D1 Hydrochloride
英文名 YN968D1 Hydrochloride
中文别名
英文别名 Apatinib Hydrochloride;YN968D-1 Hydrochloride;YN968D 1 Hydrochloride;
分子式 C24H24ClN5O 分子量 433.93
  • 用途
生物活性 Apatinib, also known as YN968D1, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.
信号通路 Angiogenesis/Protein Tyrosine Kinase 
靶 点 VEGFR RET 

结构式

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