Z-Endoxifen Hydrochloride

  • Chemical Properties
CAS No. 1032008-74-4 Cat. No. BCP16074
Name Z-Endoxifen Hydrochloride
Synonyms Endoxifen hydrochloride; Z-Endoxifen HCl; Z Endoxifen HCl; Endoxifen HCl;
Formula C25H28ClNO2 M. Wt 409.95
  • Biological Activity
Description Z-Endoxifen HCl is an estrogen receptor alpha (ERalpha) ligand, potent antiestrogen, and metabolite of tamoxifen. Z-endoxifen is the most potent of the metabolites of tamoxifen, and has the potential to be more effective than tamoxifen because it bypasses potential drug resistance mechanisms attributable to patient variability in the expression of the hepatic microsomal enzyme CYP2D6.
Pathways Hormone Pathay 
Targets Estrogen Receptor 

Structure

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