SC79
| CAS No. | 305834-79-1 | Cat. No. | BCP16070 |
| Name | SC79 | ||
| Synonyms | SC-79;SC 79; | ||
| Formula | C17H17ClN2O5 | M. Wt | 364.78 |
| Description | in vitro: SC79 is a pan-Akt activator that specifically enhances Akt phosphorylation and activation in multiple cell types and in both receptor tyrosine kinaseand GPCR-mediated signaling. SC79 not only enhances IGF1-induced Akt phosphorylation in serum-starved cells, but also elevates the level of Akt phosphorylation in cells grown in serum-rich medium. SC79-induced augmentation of Akt phosphorylation lead to enhanced Akt kinase activity. in vivo: SC79 enhances Akt activity during neuronal cell death in an mouse ischemia model (C57 Black/6). The i.p. pretreatment with SC79 in mice effectively prevents stroke induced Akt deactivation. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | AKT | ||
Structure
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