NE 100 hydrochloride
| CAS No. | 149409-57-4 | Cat. No. | BCP23907 |
| Name | NE 100 hydrochloride | ||
| Synonyms | NE-100;NE100;NE 100;NE100 HCl;NE-100 hydrochloride; | ||
| Formula | C23H33NO2.HCl | M. Wt | 392.0 |
| Description | NE 100 is a potent antagonist of sigma-1 (sigma1) receptors (IC50 = 4.16 nM). It only weakly antagonizes dopamine, serotonin, and PCP receptors, but may indirectly alter receptor activity through its effects on sigma1. NE 100 is commonly used to study the role of sigma1 receptor signaling in cells or animals. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Sigma Receptor | ||
Structure
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