Ladademstat dihydrochloride
| CAS No. | 1431326-61-2 | Cat. No. | BCP16138 |
| Name | Ladademstat dihydrochloride | ||
| Synonyms | ORY-1001 2HCl;RG6016 2HCl; RO 7051790 dihydrochloride;ORY 1001;ORY1001;RG6016;RG-6016;RG 6016;LSD1-IN-1; | ||
| Formula | C15H24Cl2N2 | M. Wt | 303.27 |
| Description | ORY-1001 is an orally available, selective inhibitor of LSD1 (IC50 < 20 nM).It targets acute myeloid leukemia (AML) stem cells and significantly reduces tumor cell load while increasing survival time in mouse models of AML. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Demethylase | ||
Structure
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