NIBR189
| CAS No. | 1599432-08-2 | Cat. No. | BCP16145 |
| Name | NIBR189 | ||
| Synonyms | NIBR-189;NIBR 189; | ||
| Formula | C21H21BrN2O3 | M. Wt | 429.31 |
| Description | NIBR-189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). NIBR-189 blocks migration of a monocyte cell line called U937, suggesting a functional role of the oxysterol/EBI2 pathway in these immune cells. | ||
| Pathways | Hormone Pathay GPCR/G Protein | ||
| Targets | GPR | ||
Structure
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