NS1619
| CAS No. | 153587-01-0 | Cat. No. | BCP23926 |
| Name | NS1619 | ||
| Synonyms | NS-1619;NS 1619; | ||
| Formula | C15H8F6N2O2 | M. Wt | 362.23 |
| Description | NS1619 is a Bkca opener or large-conductance Ca2+-activated potassium (BKCa, KCa1.1) channel activator. NS1619 pretreatment protects against shock-induced vascular hyporeactivity through PDZ-Rho GEF-RhoA-Rho kinase pathway in rats. NS1619 modulates calcium homeostasis in muscle cells by inhibiting SERCA.NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel | ||
Structure
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