Vigabatrin Hydrochloride
| CAS No. | 1391054-02-6 | Cat. No. | BCP16218 |
| Name | Vigabatrin Hydrochloride | ||
| Synonyms | γ-Vinyl-GABA hydrochloride;Vigabatrin Hcl; | ||
| Formula | C6H12ClNO2 | M. Wt | 165.62 |
| Description | Vigabatrin Hcl is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.Vigabatrin, also known as gamma-vinyl-GABA, is an antiepileptic drug that inhibits the breakdown of γ-aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA receptors. Vigabatrin is an irreversible suicide inhibitor of gamma-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the catabolism of GABA, which increases the level of GABA in the brain. Vigabatrin is a racemic compound, and its [S]-enantiomer is pharmacologically active. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | GABA Receptor | ||
Structure
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