KRCA-0008

  • Chemical Properties
CAS No. 1472795-20-2 Cat. No. BCP16229
Name KRCA-0008
Synonyms KRCA0008;KRCA 0008;
Formula C30H37ClN8O4 M. Wt 609.12
  • Biological Activity
Description KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability.KRCA-0008 is a potent dual inhibitor of Ack1 and anaplastic lymphoma kinase (ALK).
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets ALK 

Structure

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