AZ6102

  • Chemical Properties
CAS No. 1645286-75-4 Cat. No. BCP16242
Name AZ6102
Synonyms AZ-6102; AZ 6102;
Formula C25H28N6O M. Wt 428.53
  • Biological Activity
Description AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor, with IC50s of 3 nM and 1 nM, respectively, and alao has 100-fold selectivity against other PARP family enzymes, with IC50s of 2.0 μM, 0.5 μM, and >3 μM, for PARP1, PARP2, and PARP6, respectively.
Pathways Cell Cycle/DNA Damage Epigenetics 
Targets PARP 

Structure

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