R-121,919

  • Chemical Properties
CAS No. 195055-03-9 Cat. No. BCP23964
Name R-121,919
Synonyms R121919;R 121919;R-121919;NBI30775;
Formula C22H32N6 M. Wt 380.53
  • Biological Activity
Description R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.
Pathways GPCR/G Protein 
Targets CRFR 

Structure

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