NCT-501
| CAS No. | 1802088-50-1 | Cat. No. | BCP23989 |
| Name | NCT-501 | ||
| Synonyms | NCT501; NCT 501; | ||
| Formula | C21H32N6O3 | M. Wt | 416.53 |
| Description | NCT-501 is a potent ALDH1A1 inhibitor. Aldehyde dehydrogenases (ALDHs) metabolize reactive aldehydes and possess important physiological and toxicological functions in areas such as CNS, metabolic disorders, and cancers. Increased ALDH (e.g., ALDH1A1) gene expression and catalytic activity are vital biomarkers in a number of malignancies and cancer stem cells, highlighting the need for the identification and development of small molecule ALDH inhibitors. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | ALDH | ||
Structure
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