Elagolix sodium

  • Chemical Properties
CAS No. 832720-36-2 Cat. No. BCP16419
Name Elagolix sodium
Synonyms NBI 56418Na;NBI-56418 sodium;NBI56418 sodium;NBI 56418 sodium;NBI56418Na;
Formula C32H29F5N3NaO5 M. Wt 653.57
  • Biological Activity
Description Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued.
Pathways GPCR/G Protein 
Targets GnRH Receptor 

Structure

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