噁拉戈利钠
| CAS号 | 832720-36-2 | 货号 | BCP16419 |
| 中文名 | 噁拉戈利钠 | ||
| 英文名 | Elagolix sodium | ||
| 中文别名 | |||
| 英文别名 | NBI 56418Na;NBI-56418 sodium;NBI56418 sodium;NBI 56418 sodium;NBI56418Na; | ||
| 分子式 | C32H29F5N3NaO5 | 分子量 | 653.57 |
| 生物活性 | Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | GnRH Receptor | ||
结构式
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