Doxylamine succinate

  • Chemical Properties
CAS No. 562-10-7 Cat. No. BCP24067
Name Doxylamine succinate
Synonyms Decapryn; Unisom; Evigoa D;
Formula C21H28N2O5 M. Wt 388.46
  • Biological Activity
Description Doxylamine Succinate is a pyridine histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on capillaries. This drug also prevents histamine-induced pain and itching of the skin and mucous membranes.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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