DM1-SMe
| CAS No. | 138148-68-2 | Cat. No. | BCP16660 |
| Name | DM1-SMe | ||
| Synonyms | DM1-SSMe;maytansinoid derivative with ADC linker; | ||
| Formula | C36H50ClN3O10S2 | M. Wt | 783.26 |
| Description | DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Microtubule | ||
Structure
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