LY3023414
| CAS No. | 1386874-06-1 | Cat. No. | BCP16703 |
| Name | LY3023414 | ||
| Synonyms | LY 3023414;LY-3023414; | ||
| Formula | C23H26N4O3 | M. Wt | 406.48 |
| Description | LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK, extracted from patent WO/2012097039A1, compound example 1, has an IC50 of 64.9 nM, 42.1 nM, 10.6 nM, 19.1 nM for Akt1(pT308), Akt1 (pS473), P70S6(pT389), S6RP(pS240/242). | ||
| Pathways | Cell Cycle/DNA Damage PI3K/Akt/mTOR | ||
| Targets | DNA PK PI3K mTOR | ||
Structure
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