Voxilaprevir

  • Chemical Properties
CAS No. 1535212-07-7 Cat. No. BCP24118
Name Voxilaprevir
Synonyms GS-9857;GS 9857;GS9857;
Formula C40H52F4N6O9S M. Wt 868.93
  • Biological Activity
Description Voxilaprevir (GS-9857) is a noncovalent, reversible inhibitor of HCV NS3/4A protease inhibitor (PI) with pangenotypic antiviral activity. Voxilaprevir inhibits genotype 1b and 3a wild-type NS3 proteases with Ki values of 0.038 nM and 0.066 nM, respectively. Voxilaprevir is an orally active direct-acting antiviral agent (DAA) and can be used for HCV infection research.
Pathways Protease/Metabolic Enzyme Microbiology/Virology 
Targets HCV Protease HCV 

Structure

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