JH-II-127

  • Chemical Properties
CAS No. 1700693-08-8 Cat. No. BCP16207
Name JH-II-127
Synonyms
Formula C19H21ClN6O3 M. Wt 416.86
  • Biological Activity
Description JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.
Pathways Others Pathway 
Targets LRRK2 

Structure

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