Val-cit-PAB-OH

  • Chemical Properties
CAS No. 159857-79-1 Cat. No. BCP16796
Name Val-cit-PAB-OH
Synonyms
Formula C18H29N5O4 M. Wt 379.45
  • Biological Activity
Description Val-cit-PAB-OH is an precursor for making MC-​Val-​Cit-​PAB, which is also known as MC-​Val-​Cit-​PAB-OH. Val-cit-PAB-OH is a cathepsin cleavable ADC peptide linker. MC-​Val-​Cit-​PAB is useful for making ADC conjugate (antibody-drug conjugate). FDA approved drugs such as brentuximab vedotin used this linker.
Pathways Others Pathway 
Targets ADC Related 

Structure

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