Cediranib maleate
| CAS No. | 857036-77-2 | Cat. No. | BCP16806 |
| Name | Cediranib maleate | ||
| Synonyms | AZD-2171 maleate;AZD 2171 maleate;AZD2171 maleate; | ||
| Formula | C29H31FN4O7 | M. Wt | 566.58 |
| Description | Cediranib Maleate is the maleate salt of an indole ether quinazoline derivative with antineoplastic activities. Competing with adenosine triphosphate, cediranib binds to and inhibits all three vascular endothelial growth factor receptor (VEGFR-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | PDGFR VEGFR | ||
Structure
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