ZA7371
| CAS No. | 1494675-86-3 | Cat. No. | BCP16818 |
| Name | ZA7371 | ||
| Synonyms | ZA-7371;ZA 7371 TBA-7371; | ||
| Formula | C18H21N5O3 | M. Wt | 355.39 |
| Description | AZ 7371 is a non-covalent inhibitor of decaprenylphosphoryl-β-D-ribose 2’-epimerase (DprE1) with an IC50 value of 10 nM.It also inhibits PDE6 with an IC50 value of 4 μM.AZ 7371 has been shown to be active against M. tuberculosis with an MIC range of 0.78-3.12 μM and demonstrates efficacy in a rodent model of tuberculosis. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Phosphodiesterase/PDE | ||
Structure
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