Pimelic Diphenylamide 106

  • Chemical Properties
CAS No. 937039-45-7 Cat. No. BCP16854
Name Pimelic Diphenylamide 106
Synonyms RGFA-8;TC-H 106;Histone Deacetylase Inhibitor VII;
Formula C20H25N3O2 M. Wt 339.43
  • Biological Activity
Description Pimelic diphenylamide 106 has preference toward HDAC3 with Ki of 14 nM, 15 times lower than the Ki for HDAC1.Pimelic diphenylamide 106 exhibits weaker inhibitory activities against HDAC 8 with IC50 of 5 μM after a 3-h preincubation with HDAC8.
Pathways Cell Cycle/DNA Damage Epigenetics 
Targets HDAC 

Structure

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