UF 010
| CAS No. | 537672-41-6 | Cat. No. | BCP16853 |
| Name | UF 010 | ||
| Synonyms | UF-010;UF010; | ||
| Formula | C11H15BrN2O | M. Wt | 271.15 |
| Description | UF010 is a competitive inhibitor with a fast-on/slow-off HDAC-binding mechanism. UF010 induces accumulation of acetylated histones in HCT116 cells in vitro, arrests cells at G1/S transition. It inhibits proliferation of a range of cancer cell lines. UF010 activates tumor suppression mechanisms while inhibiting oncogenic pathways. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | HDAC | ||
Structure
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