Azeliragon
| CAS No. | 603148-36-3 | Cat. No. | BCP16862 |
| Name | Azeliragon | ||
| Synonyms | TTP488;TTP-488;TTP 488; PF-04494700; PF 04494700; PF04494700; | ||
| Formula | C32H38ClN3O2 | M. Wt | 532.12 |
| Description | Azeliragon , also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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