K-252A
| CAS No. | 99533-80-9 | Cat. No. | BCP16888 |
| Name | K-252A | ||
| Synonyms | K 252A; K252A; SF-2370; SF 2370; SF2370;Antibiotic K 252A; | ||
| Formula | C27H21N3O5 | M. Wt | 467.47 |
| Description | K-252A, also known as SF 2370, is an alkaloid isolated from Nocardiopisis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively). At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nmol/L). | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
Structure
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