Cariprazine HCl

  • Chemical Properties
CAS No. 1083076-69-0 Cat. No. BCP24194
Name Cariprazine HCl
Synonyms RGH-188 hydrochloride;RGH 188 hydrochloride;MP-214 HCl;RGH-188; RGH188; RGH 188; MP-214; MP 214; MP214;
Formula C21H33Cl3N4O M. Wt 463.87
  • Biological Activity
Description Cariprazine, also known as RGH-188 and MP-214, is an antipsychotic drug received FDA approval on September 17, 2015. Cariprazine acts as a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor. Action on the dopaminergic systems makes it also potentially useful as an add-on therapy in major depressive disorder. Cariprazine is approved for schizophrenia and bipolar disorder. It has also been investigated as a potential adjunct in treatment-resistant major depressive disorder.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor Dopamine Receptor 

Structure

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