Relebactam
| CAS No. | 1174018-99-5 | Cat. No. | BCP17037 |
| Name | Relebactam | ||
| Synonyms | MK-7655; MK 7655; MK7655; | ||
| Formula | C12H20N4O6S | M. Wt | 348.38 |
| Description | Relebactam, also known as MK-7655, a potent and selective β-lactamase inhibitor. At a concentration of 4 mg/L, MK-7655 reduced imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L. MK-7655 potentiated imipenem against Enterobacteriaceae with KPC carbapenemases or combinations of β-lactamase and impermeability, but not those with metallo-carbapenemases. It augmented the activity of imipenem against P. aeruginosa in general and OprD mutants in particular. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
Structure
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