ARS-853

  • Chemical Properties
CAS No. 1629268-00-3 Cat. No. BCP17042
Name ARS-853
Synonyms ARS 853;ARS853;
Formula C22H29ClN4O3 M. Wt 432.94
  • Biological Activity
Description ARS-853 is a selective, covalent KRAS(G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.
Pathways GPCR/G Protein 
Targets Ras/Rho 

Structure

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