氨基核苷嘌呤霉素
| CAS号 | 58-60-6 | 货号 | BCP17097 |
| 中文名 | 氨基核苷嘌呤霉素 | ||
| 英文名 | Puromycin aminonucleoside | ||
| 中文别名 | 维生素E醋酸酯;氨基甘嘌呤霉素;嘌呤霉素氨基核苷; | ||
| 英文别名 | ARDMA; NSC 3056; SAN; Stylomycin aminonucleoside; | ||
| 分子式 | C12H18N6O3 | 分子量 | 294.31 |
| 生物活性 | Puromycin Aminonucleoside, also known as PAN, NSC3056, is useful in the study of human glomerular disease, and glomerular function and morphology. PAN is used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeability.PAN treatment increased oxidative stress level of podocytes significantly with the induction of Nox4. Puromycin aminonucleoside increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner. | ||
| 信号通路 | Microbiology/Virology Apoptosis Pathway | ||
| 靶 点 | Antibiotic p53 | ||
结构式
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