LLY507
| CAS No. | 1793053-37-8 | Cat. No. | BCP17114 |
| Name | LLY507 | ||
| Synonyms | LLY-507;LLY 507; | ||
| Formula | C36H42N6O | M. Wt | 574.76 |
| Description | LLY-507 shows the inhibitor binding in the substrate peptide binding pocket. LLY-507 is active in cells as measured by reduction of SMYD2-induced monomethylation of p53 Lys370 at submicromolar concentrations. LLY-507 inhibits the proliferation of several esophageal, liver, and breast cancer cell lines in a dose-dependent manner. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Methyltransferase | ||
Structure
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