PFK-158
| CAS No. | 1462249-75-7 | Cat. No. | BCP17150 |
| Name | PFK-158 | ||
| Synonyms | PFK 158;PFK158; ACTPFK158; ACT-PFK-158; | ||
| Formula | C18H11F3N2O | M. Wt | 328.29 |
| Description | Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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