LFM-A13(E)
  • Chemical Properties
CAS No. 62004-35-7 Cat. No. BCP17148
Name LFM-A13(E)
Synonyms LFM A13; LFM A13；(E)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide;
Formula C11H8Br2N2O2 M. Wt 360
  • Biological Activity
Description LFM-A13 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). LFM-A13 may be useful as a new class of chemosensitizing and apoptosis-promoting antileukemic agents for treatment of patients with chemotherapy-resistant B-lineage leukemias or lymphomas.
Pathways Angiogenesis/Protein Tyrosine Kinase Cell Cycle/DNA Damage Jak/Stat Pathway Wnt/Stem Cell Epigenetics 
Targets JAK BTK PLK 
  • Publications Citing
Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats

Publications Citing of Biochempartner's LFM-A13(E)(CAS:62004-35-7)

Structure

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