Ebselen

  • Chemical Properties
CAS No. 60940-34-3 Cat. No. BCP17134
Name Ebselen
Synonyms SPI-1005;CCG-39161;SPI1005;SPI 1005; PZ 51; PZ51; PZ-51; DR3305; DR 3305; DR-3305;
Formula C13H9NOSe M. Wt 274.18
  • Biological Activity
Description Ebselen is an organoselenium compound, as an inhibitor of HIV-1 capsid CTD dimerization. Ebselen inhibits early viral postentry events of the HIV-1 life cycle by impairing the incoming capsid uncoating process.Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen is an inhibitor of inositol monophosphatase (IMPase). Ebselen permeates the blood-brain barrier and inhibits endogenous inositol monophosphatase in mouse brain.
Pathways Microbiology/Virology 
Targets HIV 
  • Publications Citing
Micelle-embedded coating with ebselen for nitric oxide generation

Publications Citing of Biochempartner's Ebselen(CAS:60940-34-3)

Structure

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