TA-01

  • Chemical Properties
CAS No. 1784751-18-3 Cat. No. BCP24229
Name TA-01
Synonyms TA01; TA 01;
Formula C20H12F3N3 M. Wt 351.33
  • Biological Activity
Description TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.TA-01 is an inducer of cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction.
Pathways Cell Cycle/DNA Damage Wnt/Stem Cell MAPK Pathway 
Targets Casein Kinase p38 MAPK 

Structure

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