Pembrolizumab
CAS No. | 1374853-91-4 | Cat. No. | BCP24244 |
Name | Pembrolizumab | ||
Synonyms | Lambrolizumab;MK-3475; | ||
Formula | C6534H10004N1716O2036S46 | M. Wt | 146 kDa |
Description | Pembrolizumab is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. In addition to Melanoma and Lung carcinoma, pembrolizumab has also demonstrated efficacy in other advanced solid tumors and hematologic malignancies. Pembrolizumab had an acceptable side-effect profile and showed antitumor activity in patients with advanced non-small-cell lung cancer. | ||
Pathways | Apoptosis Pathway | ||
Targets | PD 1/PD L1 |
Structure
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