Pembrolizumab

  • Chemical Properties
CAS No. 1374853-91-4 Cat. No. BCP24244
Name Pembrolizumab
Synonyms Lambrolizumab;MK-3475;
Formula C6534H10004N1716O2036S46 M. Wt 146 kDa
  • Biological Activity
Description Pembrolizumab is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. In addition to Melanoma and Lung carcinoma, pembrolizumab has also demonstrated efficacy in other advanced solid tumors and hematologic malignancies. Pembrolizumab had an acceptable side-effect profile and showed antitumor activity in patients with advanced non-small-cell lung cancer.
Pathways Apoptosis Pathway 
Targets PD 1/PD L1 

Structure

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