GSK481

  • Chemical Properties
CAS No. 1622849-58-4 Cat. No. BCP17262
Name GSK481
Synonyms GSK-481;GSK 481;
Formula C21H19N3O4 M. Wt 377.39
  • Biological Activity
Description GSK481 is a Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitor (RIP1 inhibitor). The recent discovery of the role of receptor interacting protein 1 (RIP1) kinase in tumor necrosis factor (TNF)-mediated inflammation has led to its emergence as a highly promising target for the treatment of multiple inflammatory diseases.
Pathways Apoptosis Pathway 
Targets RIP 

Structure

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