ML241

  • Chemical Properties
CAS No. 1346528-06-0 Cat. No. BCP17293
Name ML241
Synonyms ML-241;ML 241;CID49830260;CID-49830260;CID 49830260;
Formula C23H24N4O M. Wt 372.46
  • Biological Activity
Description ML241 inhibit p97 ATPase with IC(50) values of 100 nM. ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97 inhibitors.
Pathways Ion Channel/Membrane Transporter Cell Cycle/DNA Damage 
Targets ATPase p97 

Structure

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