Atrasentan
| CAS No. | 173937-91-2 | Cat. No. | BCP17322 |
| Name | Atrasentan | ||
| Synonyms | ABT-627; (+)-A 127722; A-147627; ABT627; ABT 627; A 127722; NSC720763; A147627; Abbott 147627; | ||
| Formula | C29H38N2O6 | M. Wt | 510.62 |
| Description | Atrasentan, also known as ABT-627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Endothelin Receptor | ||
Structure
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