Ferrostatin-1
| CAS No. | 347174-05-4 | Cat. No. | BCP17366 |
| Name | Ferrostatin-1 | ||
| Synonyms | Fer-1; | ||
| Formula | C15H22N2O2 | M. Wt | 262.35 |
| Description | Ferrostatin-1 (Fer-1) is a lipophilic antioxidant that effectively blocks ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. Fer-1 inhibited the ROS/RNS generated under rotenone insult in SH-SY5Y cells. Fourth, we revealed the effective role of Fer-1 in ER stress mediated activation of apoptotic pathway. Finally, we reported that Fer-1 mitigated rotenone-induced α-syn aggregation. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Ferroptosis | ||
Structure
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