NU 9056

  • Chemical Properties
CAS No. 1450644-28-6 Cat. No. BCP17389
Name NU 9056
Synonyms NU-9056;NU9056;
Formula C6H4N2S4 M. Wt 232.37
  • Biological Activity
Description NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.
Pathways Epigenetics 
Targets Histone Acetyltransferase 

Structure

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