IQ-1S
CAS No. | 23146-22-7 | Cat. No. | BCP17485 |
Name | IQ-1S | ||
Synonyms | 11H-Indeno[1,2-b]quinoxalin-11-one oxime;IQ 1S free acid; | ||
Formula | C15H9N3O | M. Wt | 247.25 |
Description | IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. | ||
Pathways | MAPK Pathway | ||
Targets | JNK |
Structure
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