SMER28

  • Chemical Properties
CAS No. 307538-42-7 Cat. No. BCP17486
Name SMER28
Synonyms SMER-28;SMER 28;
Formula C11H10BrN3 M. Wt 264.12
  • Biological Activity
Description SMER28 is a small molecule modulator of autophagy, inducing autophagy independently of rapamycin in mammalian cells. SMER28, acting via an mTOR-independent mechanism, prevented the accumulation of amyloid beta peptide within these cells. SMER28 may have therapeutic potential for the treatment of Alzheimer's disease and other proteinopathies.
Pathways Others Pathway 
Targets Autophagy 

Structure

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