SKF 96365 hydrochloride
| CAS No. | 130495-35-1 | Cat. No. | BCP17527 |
| Name | SKF 96365 hydrochloride | ||
| Synonyms | SKF-96365 hydrochloride;SKF96365 hydrochloride; | ||
| Formula | C22H27ClN2O3 | M. Wt | 402.91 |
| Description | SKF 96365 inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels with an IC50 value of approximately 10 μM.It inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 μM.SKF 96365 can distinguish receptor-mediated release in platelets and neutrophils from the calcium release from internal stores. However, it does not distinguish between receptor-mediated and voltage-gated release. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | TRP Channel | ||
Structure
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